منابع مشابه
Biodegradable antibiotic delivery systems.
Bacterial infection in orthopaedic surgery can be devastating, and is associated with significant morbidity and poor functional outcomes, which may be improved if high concentrations of antibiotics can be delivered locally over a prolonged period of time. The two most widely used methods of doing this involve antibiotic-loaded polymethylmethacrylate or collagen fleece. The former is not biodegr...
متن کاملBiodegradable particles as vaccine delivery systems
ii AKNOWLEDGEMENTS I would like to extend heartfelt gratitude to my teachers, colleagues and friends for their support and help that has brought this thesis research to a successful completion. I am deeply indebted to my supervisor Dr. Aliasger Salem for giving me the grand opportunity to undertake this thesis research. His awe-inspiring personality, stimulating suggestions and encouragement ha...
متن کاملBiodegradable fumarate-based drug-delivery systems for ophthalmic applications.
The function of a photocrosslinked poly(propylene fumarate) (PPF)/poly(N-vinyl pyrrolidone) (PVP) matrix for the sustained release of three ophthalmic model drugs, acetazolamide (AZ), dichlorphenamide (DP), and timolol maleate (TM), was investigated. The drugs differ in molecular weight and degree of dissociation in aqueous environments; both are parameters that significantly influence drug dif...
متن کاملthe use of natural biopolymer of chitosan as biodegradable beads for local antibiotic delivery: release studies
background chitosan is a naturally occurring biopolymer which has been widely used in a variety of biomedical applications including local antibiotic delivery due to its excellent mechanical properties, biodegradability and biocompatibility. beads are spherical, porous carriers which are prepared from various materials including chitosan. objectives the current study aimed to fabricate a new co...
متن کاملThe Use of Natural Biopolymer of Chitosan as Biodegradable Beads for Local Antibiotic Delivery: Release Studies
BACKGROUND Chitosan is a naturally occurring biopolymer which has been widely used in a variety of biomedical applications including local antibiotic delivery due to its excellent mechanical properties, biodegradability and biocompatibility. Beads are spherical, porous carriers which are prepared from various materials including chitosan. OBJECTIVES The current study aimed to fabricate a new ...
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ژورنال
عنوان ژورنال: The Journal of Bone and Joint Surgery. British volume
سال: 2011
ISSN: 0301-620X,2044-5377
DOI: 10.1302/0301-620x.93b2.24933